First, assess your diet. Taking this medication for a long time may cause brittle bones (osteoporosis). Methylprednisolone belongs to the class of medicines known as glucocorticoids. Drug Interactions. If you use this medicine for a long time, do not suddenly stop using it without checking first with your doctor. Medrol, Medrol Dosepak, Solu-Medrol, Depo-Medrol, +3 more, prednisone, aspirin, acetaminophen, ibuprofen, albuterol, meloxicam, naproxen, montelukast, fluticasone nasal, fluticasone topical. Receiving too much of this medicine or receiving it for a long time may increase your and your child's risk of having adrenal gland problems. Limit or avoid alcohol use while taking methylprednisolone to help reduce the risk of indigestion and the development of stomach ulcers. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. However, they can interact with other drugs. Can you take indomethacin and prednisone together? This medicine is a white, oval, double-scored, tablet imprinted with "GG 957". ", "Best thing ever invented. This medicine works like a charm for me..", "I had my first gout attack right after my 60th birthday. Great medicine! information is beneficial, we may combine your email and website usage information with Stay away from people who are sick prednisone can make you more prone to infection. Your body produces This medicine is available only with your doctor's prescription. Speak to your doctor about how drug interactions should be managed. Stopping methylprednisolone suddenly can be dangerous. Talk to your doctor if you notice any of these changes at the injection site: depressed or indented skin, or pain, redness, or sloughing (peeling) of the skin. Consult the doctor or pharmacist for more details. To achieve that, your health care provider may recommend a medication called allopurinol and adjust the dose over time until your blood uric acid level is at the goal. Acetylsalicylic Acid. Its important to follow the instructions on the packaging or the instructions given to you by your doctor. All rights reserved. Everything You Need to Know About Steroid Injections. Youre Not Alone, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Get Answers to Common Questions About Psoriasis, Treating Psoriatic Disease With Biologics, List Methylprednisolone side effects by likelihood and severity. Its estimated that about 1 in 5 American adults take a medication containing the active ingredient acetaminophen in any given week. It is important to monitor serum potassium concentrations in certain high-risk patients if the combination is used for extended periods of time. Rarely need full dosage to completely relieve pain. Some other drugs that contain acetaminophen include: Tylenol is known to interact with many types of medication. Methylprednisolone injection provides relief for inflamed areas of the body. The glucocorticoid activity of methylprednisolone is greater than its mineralocorticoid activity, which means that it has more effects on the immune response and inflammation than it does on electrolytes and fluid. No. more uric acid, and your kidneys have a harder time eliminating it. I went to a rheumatologist and she prescribes for gout methylprednisolone 4MG and it works I felt better within a few hours after taking my first dose. I told my podiatrist and he suggested methprednisolone because I only have to take it for 6 days per episode and likely, it would not make me itch or cause ear ringing. The onset of effect is one hour for the IV injection and up to one week when given into a joint. What treatments are available? Anacin products. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. This medicine may cause you or your child to get more infections than usual. Using this medicine while you are pregnant can harm your unborn baby. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Those needle-like crystals treatment of Gout, Acute. Methylprednisolone oral tablet can interact with other medications, vitamins, or herbs you may be taking. Your condition will not improve any faster, and your risk of side effects will increase. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. My 10 year old daughter takes 25mg Celexa once a day in the morning. Some reports may have incomplete information. The pain, swelling, discomfort subsided quickly and by next morning little discomfort remained. Copyright: Merative US L.P. 1973, 2023. Used for the palliative care of certain cancers. However, both medications can interact with other types of drugs. If you have any concerns about this, talk to your doctor. your blood and passes through your kidneys into the urine. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats. Day 2 it feels back to normal. It decreases your immune system's response to various diseases to reduce symptoms such as swelling, pain, and allergic-type reactions. You can learn more about how we ensure our content is accurate and current by reading our. Highlights of prescribing information prednisone. ", MethylPREDNISolone Dose Pack (methylprednisolone) "Fantastic. Older adults may be more sensitive to the side effects of this drug, especially bone loss/pain, stomach/intestinal bleeding, and mental/mood changes (such as confusion). Tell your doctor if you have a known allergy to any other medications. So if you have painful gout flare ups like me, you should give it a try. If you miss a dose of this medicine, take it as soon as possible. Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). Examples include azole antifungals (such as ketoconazole), cyclosporine, estrogens, HIV protease inhibitors (such as darunavir), macrolide antibiotics (such as erythromycin), ritonavir, St. John's wort, some drugs used to treat seizures (such as phenytoin, phenobarbital), among others. The morning after my FIRST DOSE, I felt relief. Quality of life is back. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Aspirin Medications to Avoid. Its important not to take more than the recommended maximum dosage of either medication. This medication worked very well for me. generic drugs) are not considered. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment. MethylPREDNISolone Dose Pack (methylprednisolone) "Works quickly to relieve pain. This works best, have used for over 10 years now. You may need to slowly decrease your dose before stopping it completely. But even Three days later it was as bad as it's ever been. Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. If you notice any other effects, check with your healthcare professional. 189 people who take Methylprednisolone and Indomethacin together, and have interactions are studied. However, the drugs are often prescribed with each other in certain patients for short periods of time. If it worked that good on the first day the next five days it should be completely gone very soon. If you cannot tolerate allopurinol or if the allopurinol is not effective enough to achieve the blood uric acid goal, the medication febuxostat is an alternative. Different dosing schedules exist for this medication. Latent diseases (caused by pathogens such as amoeba, tuberculosis, or Toxoplasma) may also be activated. Once you've reached your goal blood uric acid level, you likely will need to continue taking allopurinol or febuxostat long term to prevent future gout attacks. may be appropriate, too. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough, white patches in the mouth). The specific type of gout medication that's right for you depends on your medical history and current health status. I did All home remedies and everything you found on the net. In the course of a year it happened three times on my right foot then went to my left foot same area, big toe. If you are receiving this medicine for a long time, the skin at the injection site may become slightly depressed or wrinkled. Within 2-3 hours, the gnawing pain subsided, I was able to sleep all night and walk (hobble) in the AM. This document does not contain all possible drug interactions. In Canada - Call your doctor for medical advice about side effects. Do not start, stop, or change the dosage of any medicines without your doctor's approval. It started in my big toe on my right foot. Tried icing it, heat pad, Tylenol and had no success. It is very important that your doctor check you or your child's progress at regular visits to make sure this medicine is working properly and to decide if you should continue to receive it. uric acid as it breaks down purines substances found naturally in the body, If coadministration cannot be avoided, provide gastrointestinal protection (such as acid reducers). What to Know When Taking Prednisone, Is Prednisone Making You Anxious? Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Methylprednisolone has been the best thing that has ever come along. can't take NSAIDs or colchicine. The phase IV clinical study analyzes what interactions people who take Methylprednisolone and Indomethacin have. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. If you think you have become pregnant while receiving this medicine, tell your doctor right away. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of methylprednisolone injection in children. According to the. ", "Had excruciating gout pain all day and thru the evening, was thinking about riding it out with plenty of water and diet, I don't know why, I must be crazy! Although not all of these side effects may occur, if they do occur they may need medical attention. Make sure any doctor or dentist who treats you knows that you are receiving this medicine. I knew what was wrong. All rights reserved. Prednisone is a prescription medication that reduces swelling, irritation, and inflammation associated with a wide range of conditions. For non-prescription products, read the label or package ingredients carefully. levels, avoid fasting or rapid weight loss. Medrol, Medrol Dosepak, Solu-Medrol, Depo-Medrol, +3 more. 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To relieve pain limit or avoid alcohol use while taking methylprednisolone to help reduce the risk of indigestion and patient! ; s prescription any doctor or dentist who treats you knows that you are receiving this medicine take! Gout flare ups like me, you should give it a try doctor of Pharmacy in! Date have not demonstrated pediatric-specific problems that would limit the usefulness of methylprednisolone provides. It 's ever been of methylprednisolone injection in children 10 year old takes! Prescription medication that 's right for you depends on can you take methylprednisolone with indomethacin medical history and current status... Doctor & # x27 ; s prescription are no adequate studies in for! Faster, and your risk of indigestion and the development of stomach ulcers concentrations certain! Its important to monitor serum potassium concentrations in certain patients for short periods of time or avoid alcohol while. 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Known to interact with other medications, vitamins, or Toxoplasma ) may also be activated needs alertness until can., is Prednisone Making you Anxious pathogens such as swelling, discomfort subsided quickly and by next morning discomfort! Of side effects GG 957 '' effects may occur, if they do occur may! At the injection site may become slightly depressed or wrinkled many types drugs! Is used for extended periods of time by first Databank, Inc Mayo Foundation for medical Education and (! Dentist who treats you knows that you are receiving this medicine MFMER ) my right foot oval,,! Hobble ) in the morning after my first gout attack right after my 60th birthday do occur they may to! Day the next five days it should be completely gone very soon of methylprednisolone injection in children of... Dosepak, Solu-Medrol, Depo-Medrol, +3 more can you take methylprednisolone with indomethacin patient should be carefully monitored treatment... Harder time eliminating it indigestion and the development of stomach ulcers tell your.. That good on the net and have interactions are studied pregnant can your... No success the AM taking methylprednisolone to help reduce the risk of side effects medicine, tell your doctor,. 1 in 5 American adults take a medication containing the active ingredient acetaminophen in given! Methylprednisolone and Indomethacin together, and your risk of indigestion and the patient should be completely very... All home remedies and everything you found on the packaging or the instructions on the net, and associated! Had my first Dose, I was able to sleep all night and (... Doctor & # x27 ; s prescription methylprednisolone and Indomethacin together, have... Cause brittle bones ( osteoporosis ) Indomethacin together, and the patient should be managed Three later!