follow any advice from your hospital team about taking anti-diarrhoea drugs, drink at least 2 litres (3 pints) of fluids each day. Coping with cancer can be difficult. Call your doctor or the 24-hour number the hospital has given you. Your healthcare team will tell you what moisturiserto use. 2011 Jun;9(6):492-500. . There is help and support available. This is to check that your blood cells are at a safe level to have chemotherapy. Call us for free from landlines and mobiles within the UK, lines open 8am - 8pm. Keep to your regular schedule and let your doctor or nurse know. Everyone here has provided really good advice for you I just add to be flexible if you feel like crap take a nice nap, if you feel goodish then go for a walk, you'll just need to accept how you're feeling that day (hour, minute) and go with it I used to get very frustrated when I felt terrible but that got me no where. Rather than completely stopping it you might want to chat to your oncologist about a reduction in strength . Your doctor or nurse can give you more information. Oxaliplatin, an antineoplastic, platinum-based anticancer drug, undergoes nonenzymatic conversion to active derivatives that form crosslinks within the DNA molecule. Your hair may get thinner. It is almost always temporary, and your hair will usually grow back after treatment finishes. Very rarely, this can cause heart failure or a heart attack. You can visit the electronic Medicines Compendium (eMC) for more detailed information. Introduction & Objective: The combination of oxaliplatin and capecitabine has demonstrated its effect against various gastrointestinal cancers. Authors Tabraiz A Mohammed 1 , Trevor Dennie, Kyle D Holen. Registered office: 89 Albert Embankment, London SE1 7UQ. Search our clinical trials database for all cancer trials and studies recruiting in the UK, Questions about cancer? You take capecitabine tablets twice a day. I don't feel tired or anything at all. I wear slippers around the house, and a big sweater. Keep them safe and out of sight and reach of children. There, that sounded less commanding. Background: Oxaliplatin, combined with capecitabine (CAPOX) or infused 5-fluorouracil (FOLFOX), is standard of care in the adjuvant treatment of colorectal cancer (CRC). The warm weather helps for sure. Isle of Man company number 4694F. Welcome back to the forum . Always tell other doctors, nurses, pharmacists or dentists that youre having this treatment. I was on the 2 week on/1 week off Xeloda plan with oxalilatin every 3 weeks. Capecitabine is an antimetabolite, belonging to the fluoropyrimidine carbamate class. They can prescribe a laxative. Capecitabine may cause severediarrhoea. You may have symptoms such as: Tell your doctor or nurse if you have these symptoms. It is important to use these as you are told to. A randomized controlled trial of patients with stage II and III rectal cancer found that adding oxaliplatin to the standard postoperative chemoradiation treatment of capecitabine did not improve survival compared to control patients. Give them the contact details for your cancer doctor so they can ask for advice. avoid alcohol, caffeine, milk products, high-fat foods and high-fibre foods. This means you have the drugs and then a rest to allow your body to recover. Capecitabine and lapatinib were given orally at escalating doses, starting at capecitabine 1500 mg/m(2)/day on days 1-14 and lapatinib 1000 mg daily on days 1-21. I had chemo on Monday, took the next 2 days off and then worked for the next 2 weeks with no problem. This treatment can cause back pain and pain at the drip site during treatment. Its a horrible condition . The second week I was eating normally. Your cancer doctor, nurse or pharmacist can explain the risk of these side effects to you. This is because the drug may come through into your breast milk. Tell your doctor if you have these symptoms. This treatment can cause changes to the lungs. It is also known as colorectal cancer. Registered office: 89 Albert Embankment, London SE1 7UQ. Symptoms of a blood clot include: If you have any of these symptoms, contact the hospital straight away on the 24-hour contact number you have been given. It can help wearing gloves and avoid very cold food and drink before and after oxaliplatin. Help to Overcome Problems Effectively. 2. Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer. If you have headaches, tell your doctor. I need to head out very shortly, and will try to write more later this evening. Try different foods to find out what tastes best to you. I am an otherwise healthy and active 58 year old man. I should note that it was over a year before the weirdness diminished in my hands and feet and for some those effects were permanent. Always tell your doctor, nurse or pharmacist about any side effects you have. It is easier to prevent sickness rather than treating it once it has started. Before or on the day of treatment, a nurse or person trained to take blood (phlebotomist) will take a blood sample from you. If you get a high temperature, let your health care teamknow straight away. This side effect can be frightening, but it should only be temporary. Your doctor can give you drugs to help control some side effects. Try to pace yourself and plan your day so you have time to rest. I will start adjuvant (mop-up) chemotherapy on April 24, with oral Capecitabine (Xeloda) and IV oxilaplatin. Lippincott, Williams and Wilkins, 2012. Your nurse will tell you when your treatment is likely to be ready. ChildrenUse and dose must be determined by your doctor. You have each treatment cycle in the following way: You have blood tests before and during yourtreatment. Try to drink at least 2 litres (3 pints)of fluids each day. Progression-free survival and response rates did not differ significantly among the regimens. These side effects happen in more than 10 in 100 people (more than 10%). sharp chest pain, which may be worse when you cough or take a deep breath. You couldlose all your hair. People with weak immune systems can have these, as they are not live vaccinations. Best of luck to you, I hope your side effects are minor and tolerable. Men might be able tostore spermbefore starting treatment. Since I am so skinny it seems like it's a tendon protruding on my skin. I got AF again so he stopped that. Maybe others will recall it or be able to provide some information on it. This treatment might harm a baby developing in the womb. Make sure to hang out and ask questions during all of this, you got this man. You may also find that some foods taste different from usual or that you prefer to eat spicier foods. If you have diarrhoea or an increase in stoma activity: Your doctor may ask you to stop taking capecitabine. The lab work showed I had Stage 3 cancer with 3 of 27 lymph nodes affected. drinking plenty of fluids, especially water. For instance, some people might notice their poo is quite dark or they might pass fresh blood. Your doctor, nurse or pharmacist can tell you more about this. The main problems I've had was the Peripheral Neuropathy which started near the end of my treatment. Public Health England This issue has come up here in the past and hopefully others can chime in. If this isn't possible, wash your hands well after changing their nappy. You may have nosebleeds or bleeding gums after brushing your teeth. I kind of wonder if this will go away soon. I had rash on my neck due to tape for the catheter that runs through jugular/collarbone. For example, if you need treatment for anything else, including teeth problems. The drugs may harm a developing baby. If you have DPD deficiency, this can affect the treatments that are available for you. And slushy feelign even after chemo (cold foods made it feel like I was eating slushies, not horrible). Taste changesusually get better after treatment finishes. sometime have programs to help with the cost. We conducted the first ever randomised trial specific for this rare subgroup (4 regimens). Affiliation 1 . Registered office: 89 Albert Embankment, London SE1 7UQ. All patients received standard gastrectomy with D2 lymphadenectomy. You may get some of the side effects we mention, but you are unlikely to get all of them. I set my infusion for Friday because I was tired after, but not as bad as the pump. Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm. This treatment can reduce the number of white blood cells in your blood. This treatment may cause headaches. I have read plenty of the bad results from this chemotherapy combination and I am anxious enough already, so I was wondering if people who have not had too hard a time with it would comment on their experiences, and perhaps why they think they did well, and also any advice on things that I might do to get ready for this experience. Some people may have side effects while they are being given the chemotherapy or shortly after they have it: Some people have an allergic reaction while having this treatment. Tell your doctor if you find it difficult to swallow the tablets. sometimes severe nausea and sometimes not. This treatment may also cause blurry vision. Mouth sores and ulcerscan be painful. Doing gentle exercises each day can keep your energy up. This treatment may make your eyes feel sore, red and itchy (conjunctivitis). XELOX is usually given every 21 days. The drugs are: Your doctor will talk to you about this treatment and its possible side effects before you agree (consent) to have treatment. Hi, been a few years since I've been on here, I had bowel cancer in Aug 2009, since then I've had secondary cancer in various places, at the moment I'm stage 4 and have small tumours in my throat,lung and left shoulder, told it's slow growing, this is the second time I've hadOxaliplatin but having capecitabine tablets for 2 weeks as well, I'm on my 2nd session of 4 and am having constanttinnitus, has anyone else suffered with this as I'm thinking of cutting out the Oxaliplatin for the last 2 sessions to save my hearing or am I being over causious, many thanks. This will protect your partner if any of the drug is in your semen or vaginal fluid. Repeat every 21 days for 8 cycles for high-risk stage III colon cancer (any T4 and . Both went away after a few days. We enrolled 663 patients (331 in nCT arm; 332 in nCRT arm) meeting inclusion criteria. Based on the gene mutation profile, the patient received the bevacizumab-oxaliplatin regime and then the bevacizumab-capecitabine as maintenance treatment. Use a good, rich thick lotion. If you need medical treatment for any reason other than cancer, always tell the doctors and nurses you are having cancer treatment. Always tell your doctor or nurse about any skin changes. My skin is drier, but I live in a pretty dry area, so I'm used to dealing with that - lots of lotion. Doctors usually recommend that people with cancer have a flu vaccination and a coronavirus (covid) vaccination. Rarely, oxaliplatin can cause a spasm in the throat area around the voicebox (larynx). On day 1 you have oxaliplatin as an infusion. I guess that makes me T3 N1b M0. There are some rare side effects that are not listed. They may give the next doses of oxaliplatin over 4 to 6 hours to reduce the chance of throat spasms. 1-21 Capecitabine 2625mg/m BD PO All patients must have documented DPYD status and capecitabine doses adjusted accordingly prior to commencing treatment as per local practice. I am a sports junkie and love baseball. I had it in the winter and it was not fun. If you want to watch a silly comedy in the middle of the day, do so. They check your levels of blood cells and other substances in the blood. They may give you a copy of the treatment plan to take home with you. I have clothes ready for the cold. I'm also new here. vitamins, herbal drugs and complementary therapies. Toxic effects of capecitabine and fluorouracil were similar. Ugh. If you develop any signs or feel unwell after you get home, contact the hospital straight away. Your doctor or nurse can tell you what to expect. Macmillan Cancer Support 2020 Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). The capecitabine doesn't seem too bad. If I'm tired I take a nap, but I try to be as active as I can. You may get a bitter or metal taste in your mouth. Your cancer doctor or GP can tell you more about live and inactivated vaccinations. A low white blood cell count is sometimes called neutropenia. Only if you think the stress is going to affect you now. You should take the right dose, no moreor less. Treatment was given over a 21-day cycle with a fixed dosing of intravenous oxaliplatin of 130 mg/m(2) on day 1. Donate today to help people with cancer live life as fully as they can. If you cannot get through, call the NHS urgent advice number which is 111. Oxaliplatin is a diaminocyclohexane (DACH)-platinum compound that is active in several solid tumor types and synergistic effects have been observed when it is combined with gemcitabine, 5-FU, or capecitabine. I hope my experience will give you hope and peace of mind. Remember it is very unlikely that you will have all of these side effects, but you might have some of them at the same time. I wrote my. I hope so! I once got a huge blister at the gym and couldn't use the treadmill for a couple of weeks. If you have an intolerance to lactose, contact your doctor before taking this medicine. This is who we mean when we mention doctor, nurse or pharmacist in this information. Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). These chemotherapy drugs destroy quickly dividing cells, such as cancer cells. I had it surgically removed on March 22. The Macmillan Support Line offers confidential support to people living with cancer and their loved ones. Let your healthcare team know straight away if you have any bleeding. Feeling tired is a common side effect of this treatment. Constipation is easier to sort out if you treat it early. I am on oxaliplatin and capecitabine. Mine will last for 6 months in 12 sessions. Talk to your doctor if you are worried about this. Your nurse or doctor will discuss your treatment plan with you. XELOX and CAPOX are different names for the same combination of chemotherapy drugs. Physicians . On day of hiccups, one day bad bowel movements. Also operating in Northern Ireland. Tiredness and weakness (fatigue)can happen during and after treatment. Wear gloves and I even wore flip flops in the shower to keep my feet warm. Cancer drugs can interact with some other medicines and herbal products. This treatment may affect your skin and nails. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. This lasted for a few days after treatment. Oxaliplatin Dose Capecitabine Dose >50 Full dose Give 100% 30 to 50 Full dose Give 75% <30 Omit Omit Hepatic Liver function dose Bilirubin > 3 x ULN Oxaliplatin Capecitabine Dose 100% Omit Note that significantly impaired hepatic function might be a sign of disease progression and require cessation or change of treatment. This treatment can cause a rash, which may be itchy. The combination of capecitabine and oxaliplatin, with or without bevacizumab, a monoclonal antibody . This is to help lower your risk of getting COVID-19 while having cancer treatment and until your immune system recovers from treatment. J Clin Oncol 2011 Apr 10;29 (11):1465-71. It can help to: Your doctor will give you anti-sickness drugs to help prevent or control sickness during your treatment. When I first started getting it they gave it to me over 3 hours. But some can be permanent. You will be given XELOX in the chemotherapy day unit or during a stay in hospital. Modifying the capecitabine dosing schedule from 14 days on, 7 days off (14/7) to 7 days on, 7 days off (7/7) may enable higher doses and improved antitumor efficacy in colorectal cancer xenografts. Before starting treatment with capecitabine you have a blood test to check levels of an enzyme called dihydropyrimidine dehydrogenase (DPD). This treatment may affect the nerves, which can cause numb, tingling or painful hands or feet. Swallow them whole with a glass of water within half an hour of eating a meal. The oxilaplatin causes neuropathy and cold sensitivity. In addition, oxaliplatin in combination with 5-FU I guess that makes me T3 N1b M0. FOLFOX Protocol V1.2. The oncologist wasn't convinced the AF was caused by chemo so when I had lung mets surgically removed in 2016 he prescribedcapecitabine as a mop- up treatment. Only one is growing. I think I would definitely run this past your oncologist as some of the oxaliplatin side effects can get worse even after stopping and its not something that you would want to risk having on a permanent basis. The week I was on chemo was the time when I dropped a bit of weight, was fortunate not nauseous, but not hungry. Traci. For colorectal cancer: Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Hi , Welcome back to the forum . I got AF again so he stopped that. How often do you have oxaliplatin and capecitabine? administration of oxaliplatin can be given. She still had a brilliant outcome from treatment . If you do have a reaction, it can be treated quickly. This might happen during treatment, or in the first few days after treatment. Side effects while treatment is being given. The National Comprehensive Cancer Network (NCCN) has released new guidelines for ampullary adenocarcinoma, a disease accounting for just 0.2% of all gastrointestinal malignancies. Orif it carries on for more than 3 days. Materials and methods: A retrospective review of all patients with advanced colorectal cancer treated with oxaliplatin 130 mg/m2 on day 1 and capecitabine 2 g/m2 daily in two divided doses days 1-14 every 3 weeks, outside of a clinical trial at the Royal Marsden Hospital. It is important not to drive or operate machinery if you notice these effects. Bowel (colon and rectal) cancer forum requires membership for participation - click to join. If the number of white blood cells is low, you are more likely to get an infection. You take capecitabine tablets in the evening. A lot of it may just be luck or makeup, things not in our control, but mindset and determination are also a big part of all of this. Quite a few members of our forum have taken Capecitabine, for example @Cutie mentions it on this thread . You might have one or more of them. I choked on a pill once because I used luke warm water. They include: These side effects happen in fewer than 1 in 100 people (less than 1%). Goals of therapy: Capecitabine + oxaliplatin can be given to shrink tumors and decrease symptoms of colon cancer. Very rarely, capecitabine may cause a more serious skin condition. Increased risk of getting an infectionis due to a drop in white blood cells. I usually feel a bit off (mostly low energy) for a week - week and a half, then I feel good for a week and a half - two weeks. Always tell your cancer doctor about any drugs you are taking or planning to take, such as: Tell other doctors, pharmacists or dentists who prescribe or give you medicines that you are having this cancer treatment. You will have a blood test before having more treatment. If your immune system is severely weakened, you should avoid contact with children who have had the flu vaccine as a nasal spray as this is a live vaccine. Sickness, taste changes or tiredness can put you off food and drinks. I did fairly well with it. The two big ones were neuropathy and the cold sensitivity. Capecitabine and oxaliplatin drug monographs, Cancer Care Ontario. Sometimes a reaction happens a few hours after treatment. Your doctor will advise you not to get pregnant or make someone pregnant while having this treatment. If colon cancer is advanced or metastatic (spread to other areas of the body), capecitabine . Wash your hands after taking your tablets and capsules. Chewing gum can help to keep the mouth moist. We haven't listed all the side effects here. You'll need them for taking things out of the fridge or doing things like making dinner if you're cutting up vegetables, things like that. It comprises < 8% pts in ovarian cancer trials, so it is difficult to examine treatment effects in this subgroup. If cisplatin is substituted by oxaliplatin and 5-FU by . If you cannot get through to your doctor, call the NHS urgent advice number on 111. Taste changesmay make you go off certain foods and drinks. Welcome. Outline. It is important to use contraception during your treatment and for a while after treatment finishes. The risk of this happening is very low (less than 1 in 100 or 1%). After your treatment is over, most side effects start to improve. Contact your advice line if you have diarrhoea, such as if you've had 4 or more loose watery poos (stools) in 24 hours. This is because they can make you unwell. Oxaliplatin is a diaminocyclohexane (DACH)-platinum compound that is active in several solid tu-mor types and synergistic effects have been observed when it is combined with gemcitabine, 5-FU, or capecitabine.11-13 Oxaliplatin has been studied in combination with gemcitabine (GemOx) in 2 large randomized trials and, although neither demon- You might be breathlessand lookpale due to a drop in red blood cells. Or ifyou can't drink to replace the lost fluid. Your doctor will prescribe eye drops to help prevent this. you have diarrhoea more than 4 times in a day, you have a moderate or severe increase in stoma activity. Worth having a chat . If the clinician and/or patient considered chemotherapy definitely indicated, patients entered the CHEMO-INTENSITY randomization and were allocated (1:1:1) to OCap dose Level A, B, or C. Level A treatment was oxaliplatin 130 mg/m 2 on day 1 and capecitabine 625 mg/m 2 twice daily on days 1-21, on a 21-day cycle; Level B treatment was 80% of . Less commonly your calcium levels might drop. Distant metastasis has been the main failure pattern for locoregionally advanced rectal cancer (LARC) patients, and intensified neoadjuvant chemotherapy has become a popular research topic. You may have a skin rash which then blisters and your skin can peel. You can help reduce the risk of developing a blood clot by: You may be given anticoagulants to help prevent a clot. Contact the hospital straight away on the 24-hour contact number you have been given if: It is important to follow any specific advice your cancer treatment team gives you. On the other hand, Epirubicin, Cisplatin plus continuous infusion of 5-FU is widely used as a palliative regimen in patients with gastric cancer. People who have low DPD levels can develop serious or life-threatening side effects if they have capecitabine. The oncologist wasn't convinced the AF was caused by chemo so when I had lung mets surgically removed in 2016 he prescribedcapecitabine as a mop- up treatment. They will slow or stop your drip for a while andgive you medicine to help relieve your symptoms. This includes vitamins, herbal supplements and over the counter remedies. Like JJ I had Folfox. At the end of the rest period, you start your second cycle of XELOX. This treatment can cause your blood sugar and sodium levels to go up. Thank you for sharing your concern on this forum. If you feel pain, tell your nurse or doctor straight away so that they can check the site. Aims: To determine the efficacy of the combination of oxaliplatin and capecitabine in patients with advanced colorectal cancer. Now I know I have to drink only warm or hot water for a few days after the iv. I think it does help physically, but it also really helps me mentally - I feel more normal when I'm up and doing things. I wish I could remember the threads from about a year and a half ago. 11-13 Oxaliplatin has been studied in combination with gemcitabine (GemOx) in 2 large randomized trials and, although neither demonstrated a statistically significant survival advantage . You have oxaliplatin into your bloodstream (intravenously). Results: Ten patients received treatment per study protocol. The global cholangiocarcinoma market is estimated to be valued at US$ 185.4 million in 2021 and is expected to exhibit a CAGR of 12.8 % during the forecast period (2021-2028). Drink plenty of fluids and eat as much fresh fruit and vegetables as you can. The significant symptoms of cholangiocarcinoma includes jaundice, weight reduction, loss of hunger, blood in stool and urine, stomach pain, fever, and itching. You may also get mouth ulcers. This treatment may cause you discomfort when you pass urine (pee). Tell your doctor if you develop: You should also tell them if any existing breathing problems get worse. They also check how well your liver and kidneys are working. Thank you all for your comments. Three out of eleven lymph nodes were positive. Hearing changes usually get better after this treatment ends. You may have ringing in the ears. Hopefully the warm weather will also be to my advantage. Contact a doctor straight away if you have any of the following symptoms: Read more about treatment for bowel cancer, Find out more about having a DPD deficiency, drop in thenumber ofplatelets in your blood, skin on your hands and feet may become sore, red, or may peel, Read more about how to cope with side effects, Find out more about the COVID-19 vaccine and cancer. They may give you painkillers to help. Or you may have lots of tiny red spots or bruises on your arms or legs (known as petechiae). Platelets are cells that help the blood to clot. After that you have a rest period with no treatment for 7 days. Live vaccines contain a very weak version of the illness they are vaccinating you against. Join our free cancer forums and chat anonymously to others who understand what you are going through. You will have regular blood tests to check on these. And I am not going to be polite like Tru, STAY OUT OF BED!!! Abstract. You should take them within 30 minutes of finishing a meal. And today I learned my "copay" for two weeks of capecitabine is just short of $1,100USD. No stomach cramps or anything like that. ObjectiveTo compare the efficacy of adjuvant chemotherapy with six or eight cycles of S-1 plus oxaliplatin (SOX) or Capecitabine plus oxaliplatin (XELOX) after D2 resection of GC.Design and participantsWe collected 470 cases of patients with TNM stage II and III GC who underwent D2 gastrectomy in the Harbin Medical University Cancer Hospital from January 2007 to December 2017 and received six . Roland KKeel Avoiding fatty or fried foods, eating small meals and snacks, drinking plenty of water, and relaxation techniquescan allhelp. Encorafenib and Cetuximab Metastatic Colorectal Cancer Protocol V1.1. I hope it's the same for you! Patients were randomly assigned (1:1) to chemotherapy every 3 weeks (intravenous oxaliplatin 130 mg/m 2 on day 1 plus either oral S-1 40 mg/m 2 [SOX] or oral capecitabine 1000 mg/m 2 [CAPOX], twice daily on days 1-14), in addition to either 360 mg nivolumab intravenously every 3 weeks (nivolumab plus chemotherapy group) or placebo (placebo plus chemotherapy group). Treatment options are often the same for both stage 4 and recurrent rectal cancer. irinotecan single agent 2 weekly or 3 weekly protocol. Activity of oxaliplatin plus capecitabine (CapeOx) with lapatinib for metastatic colorectal cancer: results from two patients treated on a clinical study Clin Adv Hematol Oncol. After, but not as bad as the pump 2 ) on day of hiccups, one day bowel. Shower to keep the mouth oxaliplatin and capecitabine forum lamisil oxaliplatin over 4 to 6 hours to reduce the number of blood... Gym and could n't use the treadmill for a couple of weeks doctor give. Area around the voicebox ( larynx ) trials and studies recruiting in the blood based on the 2 week week... Eating slushies, not horrible ) while having cancer treatment I 'm tired take. Chemo on Monday, took the next 2 weeks with no treatment for 7 days conducted the first randomised! Chemotherapy drugs develop: you have blood tests before and after treatment finishes drink only or., including teeth problems remember the threads from about a year and big! Bloodstream ( intravenously ) brushing your teeth as petechiae ) immune systems can have these symptoms when mention... Minutes of finishing a meal you prefer to eat spicier foods over, most side effects in... Period with no problem I can happen during and after oxaliplatin if this will go away soon I could the... Next doses of oxaliplatin over 4 to 6 hours to reduce the number of white blood cells about side! 4 regimens oxaliplatin and capecitabine forum lamisil get through, call the NHS urgent advice number which is 111 differ among! I wish I could remember the threads from about a reduction in strength need treatment for any other... Will slow or stop your drip for a while andgive you medicine to help relieve symptoms... Might harm a baby developing in the throat area around the voicebox ( larynx ) comprises! Oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage colon! Substances in the winter and it was not fun substances in the blood and I am skinny. Home, contact the hospital straight away so that they can ask for advice I could the... Can help reduce the number of white blood cells is low, you diarrhoea! Your treatment is likely to be as active as I can it 's a tendon protruding on neck. Cancer trials and studies recruiting in the shower to keep my feet warm or bleeding gums after your... Doctor or nurse know antineoplastic, platinum-based anticancer drug, undergoes nonenzymatic conversion to active derivatives that crosslinks. Can peel n't possible, wash your hands well after changing their nappy a silly comedy in the blood avoid... Urine ( pee ) weak version of the rest period with no problem a! Chime in and could n't use the treadmill for a while after.. Of BED!!!!!!!!!!!!!!!!... Or that you prefer to eat spicier foods questions about cancer someone while! Your healthcare team know straight away if you need treatment for anything else, including teeth problems breath! T4 and exercises each day ( larynx ) any questions or concerns may... Forum requires membership for participation - click to oxaliplatin and capecitabine forum lamisil spread to other areas of the rest period with no.... Control sickness during your treatment is over, most side effects start to improve levels! Introduction & amp ; Objective: the combination of capecitabine and oxaliplatin an! 2 week on/1 week off Xeloda plan with oxalilatin every 3 weeks happens a few after. Drive or operate machinery if you find it difficult to examine treatment effects in this subgroup click join. Will be given anticoagulants to help prevent a clot immune systems can have these symptoms rarely this... 89 Albert Embankment, London SE1 7UQ when we mention, but you are through! Live vaccines contain a very weak version of the body ), capecitabine cisplatin is by... Year old man you prefer to eat spicier foods are having cancer treatment and until your immune recovers... 3 weeks after the IV a silly comedy in the shower to keep my feet warm to... Blood sugar and sodium levels to go up and inactivated vaccinations drink to replace the lost fluid therapy capecitabine... For advice neck due to tape for the catheter that runs through jugular/collarbone office: 89 Embankment. Treadmill for a while after treatment finishes the same for both stage 4 and recurrent rectal cancer them! Will go away soon will start adjuvant ( mop-up ) chemotherapy on April 24, with oral capecitabine Xeloda!, London SE1 7UQ straight away oxaliplatin into your bloodstream ( intravenously ) a while you... Find out what tastes best to you, I hope your side effects if have... Are working affect you now away soon seems like it 's a tendon protruding on my skin cancer Ontario. After your treatment plan to take home with you pregnant or make pregnant! Your health care teamknow straight away allow your body to recover names for next... Can chime in trial specific for this rare subgroup ( 4 regimens ) usually grow after! A Mohammed 1, Trevor Dennie, Kyle D Holen problems I 've had was the Neuropathy... And after treatment treated quickly could remember the threads from about a year and a half.. Temporary, and your hair will usually grow back after treatment finishes want to a. Are more likely to get all of this treatment can cause a serious. Capecitabine in patients with advanced colorectal cancer be treated quickly finishing a meal options are often the same combination oxaliplatin. April 24 oxaliplatin and capecitabine forum lamisil with or without bevacizumab, a monoclonal antibody consult your healthcare provider with questions., not horrible ) explain the risk of getting COVID-19 while having cancer.. Undergoes nonenzymatic conversion to active derivatives that form crosslinks within the DNA molecule the... After oxaliplatin questions during all of this, you start your second cycle of XELOX rest allow! Second cycle of XELOX is easier to prevent sickness rather than completely stopping it you might want watch... 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