Effects of barley green on serum lipid, MDA, SOD, ET-1 and NO of hyperlipoproteinemia rats. Hoffmann M. R., Senior P. A., Mager D. R. Vitamin D supplementation and health-related quality of life: a systematic review of the literature. A., Romieu I., Scalbert A. Impairment of IKCa channels contributes to uteroplacental endothelial dysfunction in rat diabetic pregnancy. The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease. The analogy porphyrin heads between chlorophyll (Mg) and hemoglobin (Fe) have an important therapeutic effect for chlorophyll in hemoglobin deficiency [12]. Effect of green barley leaf extract (BLE) on human platelets in vitro. Chronic disease of human beings is associated with the five evolutionary stages of the major dietary guidelines (i.e., the healthiest major dietary guidelines for modern humans): fruits or vegetables, grass or Cyperaceou, cereals (rice, wheat, millet, beans, barley, and corn), polished rice or wheat flour, and white rice or wheat flour+grass powder [10]. The following nutritional data is from the USDA. The qK1/qMg1/qCa1 region between markers Bmag0211 and GBMS0014 on chromosome 1H is shown to have large additive effects for Mg, Ca, and K concentrations in grains [54]. Cisternas P., Lindsay C. B., Salazar P., et al. An increase in K+ intake is a major nutritional approach in preventing hypertension, heart, and Alzheimer's disease as well as improving cognitive performance by decreasing inflammation and oxidative stress [10, 50]. Yamaura K., Shimada M., Fukata H., Nakayama N., Bi Y., Ueno K. Antidepressant-like effects of young green barley leaf (, Yamaura K., Tanaka R., Bi Y., et al. Barley grass powder with higher GABA, Ca, K, and tryptophan contents is a very effective functional food in promoting sleep [70]. Normal tryptophan metabolism of barley grass is a developing appropriate therapies for the symptoms of cardiovascular disease patients [126]. Huang T. T., Leu D., Zou Y. Oxidative stress and redox regulation on hippocampal-dependent cognitive functions. A. N., Liang-gang H. U. Liu G., Chen S., Zhong J., Teng K., Yin Y. Crosstalk between tryptophan metabolism and cardiovascular disease, mechanisms, and therapeutic implications. Western countries have more incident of coronary heart disease than that of stroke and diabetes for Asian countries, based on the loss of K and Mg as well as dietary fiber of major food from whole wheat to wheat flour [10]. Zeng Y. W., Du J., Yang X. M., et al. are putatively identified in healthy and diseased barley leaves, which play a role in adaptation to unfavorable growth conditions [157]. government site. BG of Yungong brand can prevent more than 20 chronic diseases, which is associated with its rich functional components, based on its growth stage from autumn via winter to summer, drying process under sunlight at 19002300m at spring with dry and windy conditions; Yunnan province at 19002300m can plant barley in the four seasons (spring, summer, autumn, and winter) and may be associated with the rich and complex enzyme system in BG. Barley grass powder for Yungong brand contains 62 times more GABA and 99 times more Ca as well as 31 times more K than that for polished rice [70]. Duthey B., Hbner A., Diehl S., Boehncke S., Pfeffer J., Boehncke W. H. Anti-inflammatory effects of the GABA(B) receptor agonist baclofen in allergic contact dermatitis. Although gluten is only found in the seeds of the barley grain, theres a risk of cross-contamination. Further researches are indispensable to resolve lots of problems, such as a better understanding of the interconnection between other 20 functional ingredients and preventing chronic diseases in clinical trials as well as ecological contribution. Park M. J., Seo W. D., Kang Y.-H. There is an important role for GABAergic, glutamatergic, and cholinergic receptors in the pathomechanism of depression [92, 93]. The mechanism of action is unknown but may be associated with the plant's antioxidant activity or its chlorophyll content. More research is needed to determine how consuming this plant could affect your blood sugar levels. Barley grass (BG) has young green leaves and stem of vegetative growth stage from seedling at 10 days after sprouting (barley sprout) to elongation stage (barley green) for nutritional peak before the start of reproductive cycle of barley [1113]; however, Vrs2 is associated with floral architecture by regulating hormonal homeostasis and gradients in barley [14]. BG extract with antioxidant and anti-inflammation can be used as natural drug for the treatment of patients with rheumatoid arthritis by scavenge ROS and downregulate TNF- production from peripheral blood and synovial fluid of patients [108]; however, green barley juice is part of arthritis therapy [109]. Seo W. D., Yuk H. J., Curtis-Long M. J., et al. GABA contents of BG for Fudamai 1 and Fan 11 are 143~183mg/100g and 125~151mg/100g, respectively [24]. Idehen E., Tang Y., Sang S. Bioactive phytochemicals in barley. BG of Yungong brand has also lustihood, bone injury recovery, antiaging, losing weight, reducing blood fat [10]. This benefit is said to be the result of its high chlorophyll content and high antioxidant content. Barley grass is rich in vitamins and minerals, has antioxidant properties, and has been shown to reduce cholesterol levels. Barley seedling extracts inhibited RANKL-induced osteoclast differentiation with alteration of IB degradation, c-Fos, and NFATc1 molecules in osteoclastogenesis [134]. However, more research in humans is needed to evaluate the effects of barley grass on weight loss. Zhang H., Zhang N. N., Ma L., Tang J., Tang Y. J. Optimization of extraction process for chlorophyll from young barley grasses based on response surface methodology. Sleep is regulated by neurotransmitter systems of GABA and dopamine signaling, which improves the sleeping quality [152]. The mis-identification of the major antioxidant flavonoids in young barley (. Antioxidant activities of lotus leaves (Nelumbo nucifera) and barley leaves (Hordeum vulgare) extracts. Here are 14 of the healthiest leafy green vegetables you. . There are greater differences of saponarin and lutonarin contents in barley leaves at the growth stage; in particular, its lutonarin content at shooting period is 6.4 times higher than that at one leaf period, and its saponarin content in two leaves at one period is 6.5 times higher than that at heading period [11]. The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect. Barley grass powder is a nutrient-dense green superfood that is made from the young leaves of the barley plant. Barley sprouts with abundant saponarin possess the liver-protective effect by inhibiting the inflammatory response induced by alcohol [69]. Plus, each serving of barley grass contains a good amount of vitamin A, a fat-soluble vitamin that regulates immune function, cell growth, and vision (2). Barley water's popularity and availability is on the rise, but does it live up to the hype? Facing cancer oneself, or supporting a loved one with cancer, is a life-altering experience that underscores just how precious life is. Vitamin D deficiency is prevalent worldwide, which can prevent diabetes, cancer, depression, and so on [63]. Flavonoids especially saponarin and lutonarin in BG have antidiabetic effect; regulate blood pressure; protect liver; have antidepressant, anticancer, anti-inflammatory, antioxidant, and hypolipidemic effects; prevent cardiovascular diseases; have antihypoxia and anti-fatigue effects; and so on (Table 2). Preparation of two flavonoid glycosides with unique structures from barley seedlings by membrane separation technology and preparative high-performance liquid chromatography. BG can prevent thrombosis and cardiovascular diseases by enhancing better blood viscosity and flow [125]. Chlorophyll and heme are the fundamental pigments of life. Diness J. G., Bentzen B. H., Srensen U. S., Grunnet M. Role of calcium-activated potassium channels in atrial fibrillation pathophysiology and therapy. Gui L., LaGrange L. P., Larson R. A., Gu M., Zhu J., Chen Q. H. Role of small conductance calcium-activated potassium channels expressed in PVN in regulating sympathetic nerve activity and arterial blood pressure in rats. . 1 box 60 capsules Sante Barley Powder in Vegetable Capsules Sant Barley is a 500-mg pure barley grass powder packed in vegetable Being rich in vitamins and minerals for the daily diet needed by the human body, Sant Barley Max helps middle-aged, health-conscious individuals enjoy a good quality of life. Barley grass juice powder may help fight carcinogens or cancer-causing substances in the body. Investigator, Howard Hughes Medical Institute. Moza J., Gujral H. S. Starch digestibility and bioactivity of high altitude hulless barley. Choi S. W., Kim S. H., Lee K. S., et al. Its also high in vitamin C, which plays a central role in everything from skin health to wound healing to oral health (3). University of Michigan Rogel Cancer Center. Three teaspoons of barley grass juice powder (5g) provide 20 calories, 2g of protein, 2g of carbohydrates, and 0g of fat. Jia Y., Zou D., Wang J., et al. Schlter T., Leide J., Conrad K. Light promotes an increase of cytokinin oxidase/dehydrogenase activity during senescence of barley leaf segments. Bo Y., Sun J., Wang M., Ding J., Lu Q., Yuan L. Dietary flavonoid intake and the risk of digestive tract cancers: a systematic review and meta-analysis. Role of bifunctional ammonia-lyase in grass cell wall biosynthesis. Zeng Y. W., Du J., Pu X. Y., Yang S. M., Yang T., Jia P. Strategies of functional food for hypertension prevention in China. Templer S. E., Ammon A., Pscheidt D., et al. Twenty-five secondary metabolites (saponarin, lutonarin, etc.) Yungong BG has the health effect due to the highest Ca content (845mg/100g) that is 99.6 times of polished rice [10, 70]. Light can promote cytokinin degradation and the formation of bioactive cytokinins in barley leaves, which has a positive correlation between cytokinin oxidase/dehydrogenase activity and senescence in most cases [16]. It has preventive as well as curing reaction against the cancer cells, which also attributes to the presence of other remedial components such as peridoxase protein and catalase enzyme. Kubatka P., Kello M., Kajo K., et al. Although barley grass is generally safe to consume for most people, there are a few side effects and precautions that you may want to consider. Bernese & Great Dane dog mom lifestyle (@greatdaneguru) on Instagram: "Happy #whatsinthebowlwednesday Today's bowl: Lamb and Turkey blend . 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